Melanocytes are pigment cells located in the surface layer of the skin called the epidermis and are responsible for producing melanin. Melanin is a dark pigment that gives skin its color and protects against ultraviolet radiation. When melanocytes stop producing melanin, the skin becomes pale, leaving areas of white patches - this is called vitiligo.
Vitiligo can start at any age, but it often occurs between the ages of 20 and 30. Vitiligo may begin on the face above the eyes, or on the neck, armpits, groin, hands or knees. Vitiligo may appear as a few small pigmented patches or spread over the entire body. In many cases, initial pigment loss will occur, then, after several months, the number and size of the light areas become stable and may remain so for a long time. Episodes of pigment loss may appear again later.
Vitiligo is present in about 1 percent of the population.
The actual cause of vitiligo is unknown, however researchers believe that there are many factors and/or conditions listed below that contribute to the disease:
- Heredity (over 30 percent of affected persons have reported vitiligo in a parent, sibling, or child)
- Exposure to chemicals such as phenol (disinfectant) or catechol (used in dyeing or tanning)
- Emotional or physical stress
- Autoimmune disorder is which the body may be destroying its own melanocytes
- Autotoxic response is which the melanocytes self-destruct leaving a toxic residue, that, in turn destroys new melanocytes
- Skin injury
- Inflammatory skin disorders
- Associative disorders such as diabetes, pernicious anaemia, hyper- and hypo-thyroidism, addison's disease(adrenal insufficiency), uveitis (inflammation of the eyes) or alopecia areata(patches of hair loss).
The symptoms of vitiligo are:
- Chalk white patches of skin often located symmetrically on both sides of the body
- White hairs within depigmented patches
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The medical history is important, but diagnosis can usually be made solely by observation of characteristic skin changes. For fair-skinned people, the doctor will use a special light, called a Wood's lamp, to shine on the skin in a dark room to identify the vitiliginous patches. In some cases, a skin biopsy may be required.
Babchi- Psoralea corylifolia Linn.
Geru- Red earth
Zanjabeel- zingiber officinale
Roscoe Shahtara- Fumaria indica Pugsley
Karafs- Apium graveolens Linn.
Gandhak Amalsar- Sulpher
Gulnar Farsi- Punica granatum Linn.
Sarphoka- Tephrosia purpurea Linn.
Atrilal- Ammi majus Linn.
Satyanasi- Argemone mexicana Linn.
Kalonji- Nigella sativa Linn.
Chiraita- Swertia chirayita Buch.Ham.
Bhangra- Eclipta prostrata linn.
Gul-e-Surkh- Rosa damascena Mill.
Parsioshan- Adiantum capillus-veneris Linn.
Compound Drugs In Unani MedicineSafoof Bars
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